2005 Symposium on Advanced Wound Care | |
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Clinical Research
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Randomized multi-center study comparing open surgical wound outcomes using silver or iodine dressings Thierry Dugre, MD, Centre Hospitalier Camille Guérin, Chatellerault, France; F. Jurczak, MD, Polyclinique de l’Ocean, Saint Nazaire, France Managing open surgical and traumatic wounds requires support of wound healing, exudate management and prevention/management of infection. Commonly used povidone iodine-impregnated gauze (PG)* has limitations, including incomplete exudate handling, painful, traumatic dressing changes and wound adherence. Advanced materials such as Hydrofiber® provide a non-adherent wound contact layer and good exudate absorption. Ionic silver incorporated into the Hydrofiber dressing (AQS)† adds antimicrobial properties. This study compared wound pain, comfort and other wound-associated parameters in open wounds managed with AQS or PG. Patients with surgical or traumatic wounds healing by secondary intent were randomly assigned to a regimen including AQS or PG dressings applied for two weeks. Pain, comfort, healing, ease of removal, and exudate management were assessed weekly. At final study evaluation, the AQS regimen was associated with less overall pain (P<0.001) and greater comfort while the dressing was in place and during dressing changes compared with PG (P< 0.001). AQS managed exudate better than PG (P<0.001) and was associated with easier dressing removal (P<0.001) and less wound-bed trauma (P=0.001) on dressing removal. Safety was similar with both treatment regimens. Protocols of care involving AQS silver-containing Hydrofiber® dressing offer an important option in the management of open surgical wounds. * Povidone iodine 10% ointment in gauze dressings. † AQUACEL® Ag with Hydrofiber®, ConvaTec, Princeton, NJ, USA. AQUACEL and Hydrofiber are registered trademarks of E. R. Squibb & Sons, L. L. C. |
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