2008 SAWC/WHS Attendee Registration

2005 Symposium on Advanced Wound Care

42
Clinical Research

The subjective evaluations of two enzymatic debridement formulations

D.W. Brett, BS, BS, MS, Smith & Nephew, Largo, FL

During development of topically applied agents, it is key to gain insight into the use & efficacy of these agents. But how does one go about gaining this knowledge? There is no better way to gain insight than by interacting directly with the clinicians that will use the agents. This was accomplished via a series of in vivo subjective performance evaluations (n=90+) performed over a period of 30 days on a new papain-urea-chlorophyllin enzymatic debridement formulations topically applied to a variety of wound types. From this evaluation it is apparent that some clinicians use the p-u-c formulations after some other type of agent or mode of debridement has been used while others use these formulations from start to finish (closure). All clinicians interviewed use these formulations until the wound is closed. All clinicians interviewed used these formulations on various types of slough; however, some clinicians do not use this type of formulation on eschar. All clinicians felt the new formulation was similar in use & efficacious to others. From this exercise it is safe to say that the new formulation is similar to others of its type currently in use.


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