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Laboratory Research
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The compatibility of a nanocrystalline silver antimicrobial dressings with various dressings types David Brett, BS, BS, MS, Smith & Nephew, Largo, FL As new and innovative wound care treatments are introduced into the market place, it is imperative to begin to investigate their compatibility with pre-existing treatments. Nanocrystalline silver-coated dressings have become popular antimicrobial barrier dressings used in wound care. In some clinical situations, a combined application of a nanocrystalline silver dressing with another type of wound care technology is required. Therefore, the impact of other wound care products on the antimicrobial activities of nanocrystalline silver dressings needs to be understood. The purpose of this study is to evaluate the antimicrobial activity by measurements of the in vitro reduction in viable bacterial counts and by the corrected zone of inhibition. Nineteen different dressing/combinations were evaluated in triplicate. The results show that by and large all products tested had no effect on the antimicrobial efficacy of the nanocrystalline silver-coated dressing with few exceptions. Only bacterial collagenase deactivated the nanocrystalline silver dressing. Sibbald RG, Williamson D, Orsted HL, et al. Preparing the wound bedÑdebridement, bacterial balance and moisture balance. Ostomy Wound Manage. 2000;46(11):14Ð35 Falanga V. Classifications for wound bed preparation and stimulation of chronic wounds. Wound Rep Regen. 2000;8:347Ð352 Schultz GS, et al. Wound bed preparation: a systematic approach to wound management. Wound Rep Regen. 2003;11:1Ð28 |
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