2008 SAWC/WHS Attendee Registration

107
Case Study

The use of bilayered cell therapy* on exposed bone to reduce osteomyelitis

James De Meo, DPM

The bi-layered cell therapy* contains multiple growth factors that are expressed in normal human skin, and it also provides cytokines and a protein matrix. A 42-year-old man with IDDM, ESRD, HTN & PVD presented with gangrene of his 3rd & 4th toes. After amputation he was left with a wound that had non-infected exposed bone. The wound healed 6 weeks after 1 unit was applied. 44 male with a revisional TMA due to Osteomyelitis left him with exposed down cuneiforms after resection of all infected bone. He healed with application of 4 units. A 68 year old male with IDDM & PVD has a traumatic crush injury to his right hallux, which caused a desquamation of his hallux. After debridement. he had exposure of his dital phalanx. He healed in 5 weeks after bone was fenestrated and application of 1 meshed unit was applied. All cases healed uneventfully

*Apligraf, Organogenesis Inc., Canton, MA



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