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Clinical Research
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Improved persistent wound pain with a novel sustained release ibuprofen and foam dressing R. Gary Sibbald, Patricia Coutts, Marjorie Fierheller Introduction.Persistent wound pain is a serious concern for most chronic wound patients. The pain may lead to reduced wound healing rates and impaired activities of daily living. Traditionally, persistent wound pain treatment has been based on oral administration of medication according to the WHO ladder for pain management, with many potential drug adverse effects. This study tested a novel safe approach with a foam wound healing dressing combined with a sustained release pain-relieving drug (ibuprofen) Methods.A comparative, open, prospective, parallel, and block-randomized study was designed. A total of 24 patients were recruited from a chronic wound clinic in Canada. Patients were randomized to a 1-week treatment period with either a foam and ibuprofen combination dressing*, or the practitionersÕ best practice local wound care dressing. The main outcome parameter was pain reduction. Results.Approximately 12 patients received each treatment option. The pain reduction results with this foam and pain medication releasing combination dressing will be compared to the local best practice. Discussion.High pain intensity can cause patient disability and potentially lead to delayed healing. A reduction in pain levels may promote faster wound healing. In addition wound pain can have a negative influence on patient well being, mobility, mental function, and sleeping pattern. The introduction of a pain medication released from a moisture balance foam dressing adds a valuable new therapeutic combination dressing to the wound bed preparation paradigm. This can lead to improved physical and mental heath status of persons with chronic wounds along with potential faster wound healing *Biatain¨ - Ibu, Coloplast A/S |
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