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Oral Abstracts (Session 3 of 5)
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Moderator: Susan Dieter, RN, MS, CWCN, CWS (Presentation 34.3) The use of low-frequency ultrasound in the treatment of chronic foot and leg ulcerations: a 51 patient retrospective analysis Steven J. Kavros, DPM, CWS, FAPWCA, Mayo Clinic College of Medicine, Department of Orthopedic Surgery and Gonda Vascular Wound Healing Center, Rochester, Minn Abstract: The study with the use of low-frequency ultrasound was initially undertaken as a feasibility study to characterize the effect of MIST therapy in a small number of lower-extremity ulcers. Due to the positive clinical outcomes, the clinical study was expanded to include 51 patients in this retrospective analysis. All patients served as their own controls. All patients had cutaneous lower-extremity ulcerations of over 3 months duration before being referred to our center. Seventy-five percent of the patients had wounds of multifactorial origin, and 75% had diabetes mellitus and peripheral arterial disease. Sixty-five percent had TcPO2 <30mmHg, and 22% had <20mmHg. As expected due to the study design, the initial area of the baseline wounds were larger than the initial measurements of the MIST therapy wounds (mean = 2,477mm3, sd = 4,979mm3 vs. mean = 1,609mm3, sd=3,395mm3, respectively). The mean treatment time for the baseline SOC and MIST therapy wounds were 9.6 weeks and 5.5 weeks, respectively. The mean percent reduction in wound size (SOC = 37.3%, MIST = 94.4%) and the weekly reduction in area (SOC = 91.2mm3, MIST = 318.0mm3) were significantly higher in the MIST arm than in the SOC arm, and both were statistically significant (p=0.05). References 1. Gogia PP. Physical therapy modalities for wound management. Ostomy Wound Manage. 1996;42(1):46–8, 50–52, 54. 2. Environmental Health Criteria 22. Published under joint sponsorship of the United Nations Environmental Problems, the International Labor Organization and the International Radiation Protection Association, World Health Organization, Geneva, 1982. 3. Young SR, Dyson M. Effect of therapeutic ultrasound on the healing of full-thickness excised skin lesions. Ultrasonics. 1990;28(3):175–180. 4. Harvey W, Dyson M, Pond JB, Grahame R. The stimulation of protein synthesis in human fibroblasts by therapeutic ultrasound. Rheumatol Rehabil. 1975;14(4):237. 5. Oyson M. The effect of ultrasound on the rate of wound healing and the quality of scar tissue. Proceedings of the International Symposium on Therapeutic Ultrasound. CPA, Winnipeg, 1981. 6. Jackson BA, Schwane JA, Starcher BC. Effect of ultrasound therapy on the repair of Achilles tendon injury in rats. Med Sci Sports Exerc. 1991;23(2):171–176. 7. Bacharach JM, Rooke TW, Osmundson PJ, Gloviczki P. Predictive value of transcutaneous oxygen pressure and amputation success by use of supine and elevated measurements. J Vasc Surg. 1992;15(3):558–563. 8. Palumbo PJ, Melton LJ. Peripheral vascular disease and diabetes. In: Diabetes in Americans. Washington, DC: US Government Printing Office, 1985. NIH Publication 85-1486. 9. Pecoraro RE, Reiber GE, Burgess EM. Pathways to diabetic limb amputation: basis for prevention. Diabetes Care. 1990;13(5):513–521. 10. American Diabetes Association. Diabetes 1996 Vital Statistics. Alexandria, Va: American Diabetes Association, 1996. |
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